6 reported that UCA1 promotes the progression of oral squamous cell carcinoma by activating the WNT/β‐catenin signaling pathway. Xiao et al. 7 demonstrated that UCA1 promotes epithelial‐mesenchymal transition (EMT) of breast cancer cells by enhancing the Wnt/beta‐catenin signaling pathway. UCA1 promotes the progression and regulates proliferation through the KLF4‐KRT6/13 signaling pathway in prostate cancer 8. UCA1 has been shown to be a novel diagnostic and predictive biomarker in plasma for early GC 9. TGFβ1 induces the upregulation of UCA1, which promotes invasion and migration in GC 10. This evidence concerns the gene UCA1 and oral cavity squamous cell carcinoma.