NF‐κB inhibitor reversed the acidic bile (pH 4.0) induced deregulation of the analysed miRNA markers by preventing up‐regulation of “oncomirs” and inhibiting the down‐regulation of “tumour suppressor” miRNAs, in treated HHPC (Figure 2) and HHK (Figure 3). Here, NFKB1 is linked to neoplasm.