The reversal of miRNA phenotypes, by NF‐κB inhibitor, was particularly intense in acidic bile‐treated HHPC, demonstrating a significant decrease in expression ratios of “oncomirs” (Figure 4A‐a) and increase in expression ratios of “tumour suppressor” miRNAs (with/without BAY 11‐7082), compared to control (P = .0269, one‐way ANOVA; by Kruskal‐Wallis) (Figure 4A‐b). Here, NFKB1 is linked to neoplasm.