For example, an autocrine induction of cellular proliferation was observed in chronic myeloid leukemia (Raimondo et al., 2015) and in human gastric cancer (Qu et al., 2009; Pan et al., 2017) through, for instance, the phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) and MAPK/ERK signaling pathways (Qu et al., 2009) and transference of a long noncoding RNA (Pan et al., 2017). The gene discussed is AKT1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.