Finally, to evaluate the anti-MM activity of syringolog-1 against Btz-resistant MM cells, NOD SCID mice subcutaneously inoculated with Btz-resistant MM cells, OPM-2/Btz were administered with syringolog-1 intraperitoneally, twice weekly, at 5 mg/kg. The gene discussed is CASC3; the disease is Miyoshi myopathy.