Focusing only on the PSMA expression in the neovasculature of malignant thyroid diseases, we noted that the neovasculature of undifferentiated thyroid cancers (poorly-differentiated and anaplastic carcinoma) showed strong PSMA expression in 8/10 (80.00%) cases, while high neovascular PSMA was only rarely observed in differentiated carcinomas (papillary, follicular and medullary thyroid cancers) (11/53 or 20.8% of cases; p = 0.0006, Fisher ́s exact test). Here, FOLH1 is linked to medullary thyroid gland carcinoma.