In our immunohistochemical assessment, PSMA expression in the neovasculature was found to be positive in 5/38 benign thyroid diseases (13.2%): 0/18 Sporadic nodular goiter, 2/9 follicular adenoma, 1/2 hyalinising trabecular thyroid tumor, 1/3 Grave ́s Disease, 1/2 Lymphocytic thyroiditis, 0/1 Granulomatous thyroiditis, 0/3 unspecific thyroiditis. This evidence concerns the gene FOLH1 and nodular goiter.