RAB39A and cancer: In order to identify the downstream pathways of RAB39A, which ultimately affect cancer stemness, we used RNA-seq to screen the RNA profile of spheres formed by 143B and HeLa cells with knockdown of RAB39A. We compared transcription patterns in spheres obtained by silencing RAB39A (shRAB (4) and (5)) with spheres from parental cells, spheres from RAB39A-overexpressing cells (RAB39), and with control cells (shCont and V5, which are shRABs and RAB39 controls, respectively).