Park et al., in a retrospective study showed that all of the 225 cases of metastatic colorectal carcinoma to the ovary were CK7-/CK20+ and only one case was CK7-/CK20-; 75% of low-grade and 52% of high-grade carcinomas were CK7-/CK20+ (5). This evidence concerns the gene KRT7 and carcinoma.