TNF and tuberculosis: The strongest evidence for the role of TNF-α to prevent TB pathogenesis was well reported in patients treated with TNF-α antagonist (Keane et al., 2001; Gardam et al., 2003; Askling et al., 2005; Wong et al., 2007a; Wallis, 2008; Martin-Mola and Balsa, 2009; Yasui, 2014).