Furthermore, over-expression of the oncogenic form of EGFR (EGFRvIII) under the promoter S100b, a non-stem cell marker (Raponi et al., 2007), induced gliomas recapitulating the pathological features of human oligodendroglioma (Weiss et al., 2003; Persson et al., 2010). The gene discussed is S100B; the disease is oligodendroglioma.