PRKN and Parkinson disease: The most commonly identified genetic mutations linked to heritable PD were found in the genes SNCA and LRRK2, responsible for an autosomal-dominant forms of PD, and in Parkin, PINK1, DJ-1, and ATP13A2 which account for PD with autosomal recessive mode of inheritance (Klein and Westenberger, 2012; Ferreira and Massano, 2017).