Intra-tumoural hENT1 expression was confirmed to be a predictive marker for gemcitabine treatment, and the additional prognostic value of DPD tumour expression may be used to estimate the survival in patients with low hENT1 tumour expression, where low DPD tumour expression indicates better prognosis at least for patients treated with 5FU/FA. The gene discussed is SLC29A1; the disease is neoplasm.