GLS and non-small cell lung carcinoma: In our previous work, we reported that GAC activity in breast cancer cells can be regulated by NF-κB.12 To determine whether the GAC activity in NSCLC cells can also be regulated by NF-κB, we performed another isoelectric focusing experiment and found mobility-shifted phosphorylated spots were diminished when NF-κB (p65) was depleted from H1299 cells (Fig. 4a).