ASXL1 and medullomyoblastoma with myogenic differentiation: In univariate analysis, ASXL1 and SRSF2 mutations, absence of CALR type 1/like, unfavorable karyotype, circulating blasts ≥2%, older age, and the failure to achieve CI were all associated with inferior post-MMB survival (p < 0.05 in all instances).