CRLF1 and cancer: Among these genes, we found that cytokine receptor-like factor 1 (CRLF1) had a higher fold-change in cancer tissues than in paired normal tissues (average fold-change: 22.54, P < 0.001) and a higher fold-change in late-stage cancer tissues than in early-stage cancer tissues (average fold-change: 2.178, P < 0.01).