Thus, miR-106-5p was speculated to be the miRNA that binds to both NEAT1_2 and the 3′ UTR of ATAD2. MiR-106b-5p, as a member of the miR-106b-25 cluster, has been confirmed to promote cancer cell proliferation and metastasis in prostate cancer, esophageal squamous cell carcinoma, and gastric cancer41,42. Here, ATAD2 is linked to Familial prostate cancer.