NFE2L2 and renal fibrosis: Recent studies using the UUO model have shown that adenosine levels (Tang et al., 2015), nuclear factor-erythroid-2-related factor 2 (Nrf2) (Chung et al., 2014), interleukin-10 (Jin et al., 2013), and the JAK/STAT signaling pathway (Koike et al., 2014) are related to renal fibrosis, thus offering a potential therapeutic target for renal injury.