They are different regarding percentage of patients with liver cirrhosis (10.0 vs. 79.2%, p < 0.001), CTP score (percentage of class C, 9.2 vs. 0%, p < 0.001), and AFP level (percentage of patients with AFP greater than 400 ng/ml, 23.5 vs. 10.0%, p < 0.001). The gene discussed is AFP; the disease is cirrhosis of liver.