Consistent with the meta-analysis, the results from database showed that high CD73 expression was significantly correlated with poor OS in breast [HR: 1.23 (95% CI: 1.11–1.38); P < 0.05; Fig. 4b] and ovarian cancer [HR: 1.14 (95% CI: 1.00–1.29); P < 0.05; Fig. 4e]. Here, NT5E is linked to ovarian cancer.