Consistent with our findings, a large single-centre study has also shown that both spot and 24-h measures of albumin and protein excretion were similar predictors of doubling of serum creatinine, transplant loss and death.(18) The results of the current study are therefore in-line with previous studies in various CKD populations demonstrating that spot urine protein ratios provide valuable prognostic information. The gene discussed is ALB; the disease is chronic kidney disease.