CXCL8 and type 2 diabetes mellitus: Based on the aberrant high baseline levels of IL-8, we predict that T2D induces a frequent but unhealthy cooperation between these cells contributing to chronic low-grade inflammation; in the presence of the bacillus, however, this cooperation is disrupted due to the shutdown of IL-8 production, as observed in MFs derived from patients with T2D, leading to the consequent potential arrest of neutrophil influx.