ETS1 has also been implicated in T cell maturation arrest in T‐ALL.34 IKKα, which is a subunit of the IkB kinase (IKK) complex, activates nuclear factor‐kB (NF‐kB); ETS1 transactivates IKKα in EU‐4,43 which is a B‐cell precursor ALL cell line. The gene discussed is CHUK; the disease is acute lymphoblastic leukemia.