The DHX15 gene (alias PRP43) is a member of the DEAH‐box family and is located on the minus strand of chromosome 4 (4p15.3).16 Recent evidence has suggested that DHX15 may contribute to carcinogenesis, and overexpression of DHX15 has been observed in lung adenocarcinoma samples.17, 18 Semiquantitative RT‐PCR analysis showed up‐regulation of DHX15 in breast cancer cells. Here, DHX15 is linked to breast carcinoma.