ITGA3 and neoplasm: Furthermore, a research of the relevance between the expression of ITGA3 and clinicopathological features in the 46-patient cohort showed that high expression of ITGA3 was significantly associated with large tumor size (P = 0.034), the presence of lymph node metastasis (P = 0.034), and advanced tumor stages (P = 0.027) (Table 1).