Interestingly, p73 protein exhibited a different accumulation pattern, with two peaks appearing at 4 and 24 hpi (Fig. 1a), which was also observed in p53-depleted H1299 human lung carcinoma cells, but not in Saos2 human osteogenic sarcoma cells lacking both endogenous p73 and p53 proteins (Fig. 1b). This evidence concerns the gene TP53 and lung carcinoma.