GK and infection: Previously studies showed that the lack of expression of gB, gH, or gL alone has drastically effect on viral maturation, which is necessary for viral replication, while HSV-1, EHV-1 or other alpha-herpesvirus could replicate and produce infection progeny virus without the expression of other glycoproteins, such as such as gE, gI, gK and so on22–24.