One of these variants, rs17696696[G] intronic to CFDP1, associates with AS in these samples and was thus tested in additional 2,115 AS cases and 28,121 controls; the joint analysis yielded OR = 1.07, 95% CI: 1.03–1.11, P = 0.00013 (Table 3). Here, CFDP1 is linked to aortic valve stenosis.