Like the LPA variant, rs1830321 in TEX41 associates with CAD in Iceland (OR = 1.05, 95% CI:1.03–1.08; P = 9.3 × 10−5), but the MYH6 missense variant and rs7543130 near PALMD do not (Table 2 and Supplementary Data 2). Here, TEX41 is linked to coronary artery disorder.