The swabs from the tonsillitis patients have higher concentration of IgG compared with the swabs from the healthy volunteers, mostly pronounced for IgG1, because of increased plasma leakage as shown in Fig. 4 This increase in plasma leakage was supported by the elevated levels of several other high abundant plasma proteins such as albumin and fibrinogen in the swabs from the tonsillitis patients (Figs. 4B and 5A). This evidence concerns the gene ALB and medical procedure.