The FPG and PPG measurements together with HbA1c value provide some information for the physician to choose an insulin type by following simple ratios: ratio of prandial and FPG index ([PPG – FPG]/FPG); a high ratio implies a higher prandial component, which will require premixed or rapid-acting/short-acting insulin, while a low level suggests a greater contribution of the fasting component of hyperglycemia and supports the use of basal insulin. The gene discussed is INS; the disease is Hyperglycemia.