INS and type 2 diabetes mellitus: Key areas in insulin therapy discussed in the guidelines include insulin regimen in patients with T1DM, a stepwise approach to insulin initiation, titration, and intensification in patients with T2DM, self-monitoring of blood glucose (SMBG), awareness and management of hypoglycemia, weight gain with intensive insulin therapy, and the role of psychosocial aspects associated with insulin therapy in diabetes care.