Abbreviations: AMM: amelanotic malignant melanoma; BCC: basal cell carcinoma; C: case; CD30+ LD: CD 30+ lymphoproliferative disorder; CR: current report; FDE: fixed drug eruption; L: left; LH: lymphoid hyperplasia; LP: lichen planus; LPPD: lichenoid pigmented purpuric dermatosis; PAT: purpura annularis telangiectoides; R: right; Ref: reference; SCCis: squamous cell carcinoma in situ; THH: targetoid hemosiderotic hemangioma. The gene discussed is TNFRSF8; the disease is lymphoproliferative syndrome.