Other alternative diagnoses, based on the appearance of the lesion (each in one patient), included actinic keratosis, amelanotic melanoma, angioma, bite, CD30+ lymphoproliferative disorder, fixed drug eruption, irritated nevus, Kaposi sarcoma, lichen planus, lichenoid pigmented purpuric dermatosis, solar purpura, squamous cell carcinoma in situ, and vasculitis. The gene discussed is TNFRSF8; the disease is nevus.