FN1 and breast cancer: Collagen-based scaffolds supported directional metastasis of BC cells with invasive phenotypes compared to Matrigel or RADA16 peptide scaffolds, which could be enhanced by the increased collagen density.83–85 A bovine serum albumin (BSA) scaffold with fibronectin (FN) showed desirable BC cell adhesion and migration compared with the BSA scaffold alone.86