CCL18 and cancer: The result from the wound healing assay showed that miR-622 suppressed OS-RC-2 and ACHN cell migration stimulated with CCL18 (Fig. 4c–e) Transwell system was used to observe the cell invasion ability and the result showed that the invaded cells became less in the group of cells with miR-622 than the controls and miR-622 also decrease cell invasion of CCL18-overexpressed cancer cells (Fig. 4f–h).