Immunohistochemistry using an anti-SAS1B monoclonal antibody (mAb) (6B1; shown to largely recognize cytoplasmic SAS1B) was performed on a TMA containing primary and metastatic pancreatic cancer samples, pancreatic intraepithelial neoplasia (PanIN; precursor lesions), and normal duct from both benign and malignant pancreas. Here, ASTL is linked to cancer.