AFP and hepatocellular carcinoma: Multivariate analysis was performed using the Cox Proportional hazards model and the analysis revealed that AFP, tumor number, and tumor size were independent prognostic factors for HCC (all P < 0.05), while GSTP1 was not an independent prognostic factor for OS (HR: 0.715, 95% CI: 0.510-1.003, P = 0.052) and DFS (HR: 0.859, 95% CI: 0.602-1.226, P = 0.403) in HCC patients.