Remarkably, tumor-specific positive LMO2-correlated genes were enriched in Ribosome and Extracellular matrix (ECM) receptor interaction while negative LMO2-correlated genes were specifically enriched in some tightly cancer-related pathways, including cellular senescence, stemness regulating pathway, ErbB (Her2) pathway, Estrogen pathway and central carbon metabolism in cancer. This evidence concerns the gene EGFR and cancer.