AKT1 and neoplasm: Notably, the tumor-normal common positive LMO2-correlated genes were also enriched in the negative regulation of apoptosis and positive regulation of EMT, JAK-STAT, PI3K-AKT, Notch and cytoskeleton remodeling (Rho protein) pathway, while the normal-specific positive LMO2-correlated genes were particularly enriched in the negative regulation of cell cycle G2/M phase transition (Figure 2D).