MUC5AC and ulcer disease: In another study performed by Mota da Silva et al. [34], an hydroalcoholic extract of Maytenus robusta reduced the gastric ulcer area by 53%, and the healing effectiveness seemed to be mediated by increased gastric mucin content and reduced oxidative stress and inflammatory parameters at the site of the ulcer; nevertheless, it seems that the extract did not reduce the leukocyte migration as in the case of CpMet.