Several of these miRNAs target key transcriptional regulators, such as Bcl6, the signal transducer and activator of transcription 3, Parkinsonism associated deglycase (MiR-544 (ref. 68, 69)), RUNX3 (MiR-532-5p and miR-628 (ref. 70)). The gene discussed is RUNX3; the disease is Parkinson disease.