HSP90AA1 and cancer: In many types of cancer, HSP90 and other components of the molecular chaperone network are overexpressed, enabling the maturation of many mutant proliferative signaling kinases and transcription factors (i.e., oncoproteins), thereby contributing to the growth factor independent growth and unregulated proliferation that are two of the hallmarks of cancer (Jarosz 2016; Calderwood and Gong 2016; Wu et al. 2017).