ERVW-1 and infection: Interestingly, BLd-H77 was able to inhibit, in a dose-dependent manner, infection of Huh7.5 cells by replicative hepatoma cell line-derived HCV particles (HCVcc) harboring envelope glycoproteins of gt1a (H77/JFH-1) but also gt2a (JC1) (Fig 4F; S11A Fig).