VDR and Insulin resistance: The present study determined that PPARD mutation is associated with type 2 diabetes in Han nationality.[23] Second, there is a potential relationship between vitamin D and vitamin D receptor genetic polymorphism and insulin resistance in patients with vitamin D deficiency.[24] In addition, the risk of vitamin D is negatively correlated with type 2 diabetes, which may be due to the clinical medium, which is related to c-reactive protein, interleukin 6, and soluble intercellular adhesion factor 1.[25–28]