Some data indicates that RET c.2372A > T is associated with familial medullary thyroid carcinoma (FMTC), hereditary cancer-predisposing syndrome, Hirschsprung disease, multiple endocrine neoplasia (MEN) including types 1, 2a, 2b, and 4, pheochromocytoma, and renal adysplasia [4, 48, 49]. Here, RET is linked to Hirschsprung disease.