SOX2-OT and neoplasm: Univariate Cox proportional hazards regression model analysis revealed a statistically significant correlation between the OS rate of NSCLC patients and SOX2OT level (P = 0.009), ANRIL level (P = 0.019), tumor size (P < 0.001), lymph node metastasis (P < 0.001), and TNM stage (P < 0.001) (Table 2).