In support of the results from the in vitro mechanistic study, we found that patients with metastatic PCa had significantly higher levels of Glo1 and TGF‐β1 and markedly lower levels of MG‐H1, AP and miR‐101 compared with patients exhibiting non‐metastatic PCa (Table 2). This evidence concerns the gene GLO1 and posterior cortical atrophy.