2011). These changes showing evidence that rhEPO results in impaired endothelial function, increased total peripheral and renal vascular resistance together with a systemic procoagulant state. EPO has been linked to hypertension, sudden death after stroke, myocardial infarction, and pulmonary embolism in elite athletes (Pope et al. 2014) which these findings support. This evidence concerns the gene EPO and pulmonary embolism.