MTM1 and metabolic dysfunction-associated steatohepatitis: We previously utilized several S. mutans strains with expression of Cnm and PA on the cell surface, which demonstrated that intravenous administration of a Cnm-positive PA-positive S. mutans strain to 6-week-old C57BL/6J mice induced NASH-like findings at 12 weeks and that the expressions of interferon-gamma considered to induce immune responses and metallothionein associated with oxidative stress were elevated in liver tissue [16,17].