For instance, while Nlgn1 is found preferentially in excitatory and Nlgn2 in inhibitory and cholinergic synapses,26,27 Nlgn3 localizes at both excitatory and inhibitory synapses.28–32 Nlgn4X has been observed in inhibitory glycinergic synapses.33 Currently, mice expressing Nlgn3 mutated forms display autism-like behaviors and are highly sought as experimental models for the study of ASD pathology.34,35. This evidence concerns the gene NLGN3 and autism.