Moreover, GLP2 exhibits a protective effect on hepatic ischemia-reperfusion injury in rats,11 and GLP2 agonists decrease the need for parenteral nutrition (PN) in short bowel syndrome (SBS).12, 13 Furthermore, the absence of a motif in GLP2 could be the reason for a significantly lower strength of interaction between GLP2 and heparin in inducing protein aggregation.14 This evidence concerns the gene GCG and macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss.