Radiolabeled monoclonal anti-CD105 antibodies or scFv-binding have been reported to significantly enhance tumor uptake and permit efficient tumor visualization in xenograft animal models by using positron emission tomography (PET), single photon emission computed tomography/computed tomography (SPECT/CT) [6–8], or PET/near-infrared fluorescence (NIRF) imaging [9, 10]. The gene discussed is ENG; the disease is neoplasm.