PTH and obesity due to melanocortin 4 receptor deficiency: Given the presence of brachydactyly and short stature, TRPS could be confused with the AHO phenotype, especially so if obesity (or overweight) and/or PTH resistance [37] and another hormone imbalance (GH deficiency has also been reported in some TRPS cases [43–47]) appear in the clinical profile, as shown in our two previously published cases [33] reviewed here.