Larsen et al. applied MHCI tetramers with CMVpp65 peptides, and PBMCs from SLE patients (n = 21) and HCs (n = 15), and showed normal amounts of CD8 CMVpp65-specific T-cells in SLE patients with normal cytokine responses upon CMV stimulation [26]. This evidence concerns the gene CD8A and systemic lupus erythematosus.