LGALS1 and neuroblastoma: Splenocytes from A/J mice receiving syngeneic NXS2 neuroblastoma cells with down-regulated Gal-1 (Gal-1 low) secreted higher amounts of IFN-γ and displayed enhanced cytotoxic T-cell function compared to NXS2 control cells or NXS2 cells overexpressing Gal-1 (Gal-1 high) [50].