In the same year, Bertucci et al. (2004) compared 50 cancerous and noncancerous colonic tissues using a DNA microarray consisting of ~8000 spotted human cDNAs, in the process discovering that Guanine nucleotide binding protein subunit beta2 like-1 (GNB2L1), also named as RACK1, was the top-ranked gene overexpressed in cancer samples [23]. This evidence concerns the gene RACK1 and cancer.